Watford's Troy Deeney has scored six goals and provided four assists in 2019 Holebas suffered a hamstring injury during the FA Cup semi-final win
Holebas suffered a hamstring injury during the FA Cup semi-final win over Wolves, Quina has a shoulder injury and Cleverley a calf problem.
Arsenal’s Sokratis Papastathopoulos begins a two-match ban for accumulating 10 bookings.
Granit Xhaka has a groin injury and will be assessed ahead of the game, while Danny Welbeck, Rob Holding and Hector Bellerin remained sidelined.
Watford manager JaviGracia says the FA Cup final won’t be a distraction: “I am only thinking about trying to win the next game. I don’t want to think any further.
“We have good professionals and, with these players, it is easy as they know the next game is very important.
“We don’t have only one final – we have seven finals. All of them are focused on the next game.”
Arsenal head coach Unai Emery: “Each match gives us a big challenge for the possibility to improve and take three points and the possibility to end the season in the top four.
“For us that would be a big success. When we started last in the table after the first two matches in the season we were thinking about arriving in this moment with the possibility of being in the top four in our hands.”